MIPdatabase
Authors: Wang L, Zhang ZJ
Article Title: The study of oxidization fluorescence sensor with molecular imprinting polymer and its application for 6-mercaptopurine (6-MP) determination.
Publication date: 2008
Journal: Talanta
Volume: 76
Issue: (4)
Page numbers: 768-771.
DOI: 10.1016/j.talanta.2008.04.024
Alternative URL: http://www.sciencedirect.com/science/article/B6THP-4SB7TSB-9/1/17e8deeceb1d2259ac5753de0d1dcc2f
Abstract: This paper developed optical fiber sensor based on molecular imprinted polymer as artificial recognition element for the determination of 6-mercaptopurine (6-MP) in human serum. This approach displayed high sensitivity by oxidizing 6-MP to a strong fluorescent compound with H2O2 in the alkaline media. It offered a relatively nice selectivity for 6-MP detection by molecular imprinted polymer's recognition. The relative standard deviation (R.S.D.) was 5% for a same sensor (n = 5) when 6-MP concentration was 1.0 x 10-7 g mL-1 in serum. The developed method was satisfactorily applied to the determination of 6-MP in human serum without any necessity for sample treatment or time-consuming extraction steps prior to the analysis
Template and target information: 6-mercaptopurine, 6-MP
Author keywords: 6-Mercaptopurine, optical fiber sensor, molecular imprinted polymer, Oxidation fluorescence
Join the Society for Molecular Imprinting
New items RSS feed
View latest updatesSign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.
Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
