MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Zhang JK, Wang H, Liu WS, Bai LR, Ma N, Lu JH
Article Title: Synthesis of Molecularly Imprinted Polymer for Sensitive Penicillin Determination in Milk.
Publication date: 2008
Journal: Analytical Letters
Volume: 41
Issue: (18)
Page numbers: 3411-3419.
DOI: 10.1080/00032710802568671
Alternative URL: http://www.informaworld.com/10.1080/00032710802568671

Abstract: Penicillin G (PG) in milk is unsafe for human and is a big problem for the foods industry. Hence, the better analytical and eliminative techniques are demanded. We investigated a PG molecular imprinted polymer (MIP), which can sensitively detect and extract the PG from milk and other samples. The MIP synthesis involved a β-lactam antibiotics PG, methacrylic acid (MAA) and dimethyl formamide (DMF). Its properties were analyzed with Scatchard plot, which showed that there were two affinity sites of the PG polymer. The first equilibrium dissociation constant of the high-affinity binding sites Kd1 was 1.14 x 10-4 mol/L and the binding capacity Qmax1 was 46.01 μmol/g; the second equilibrium dissociation constant of the low-affinity binding sites Kd2 was 1.35 x 10-3 mol/L and the binding capacity Qmax2 was 72.55 μmol/g. Furthermore, two PG determination methods using the polymer were developed. The first was carried out quantitatively with a spectrophotometer and the detection limit was 1-Šppm. The other one was the combination of the MIP particles with milk fermentation for PG analysis and the sensitivity was 10 ppb
Template and target information: penicillin G, beta-lactam antibiotic, PG
Author keywords: determination, extraction, milk, molecular imprinting polymer, penicillin

  Eat, sleep, imprint, repeat mug  SMI logo mug  Woman of proper-tea mug in blue

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner