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Reference type: Journal
Authors: Li MKY, Lei NY, Gong CB, Yu YJ, Lam KH, Lam MHW, Yu HX, Lam PKS
Article Title: An organically modified silicate molecularly imprinted solid-phase microextraction device for the determination of polybrominated diphenyl ethers.
Publication date: 2009
Journal: Analytica Chimica Acta
Volume: 633
Issue: (2)
Page numbers: 197-203.
DOI: 10.1016/j.aca.2008.11.060
Alternative URL: http://www.sciencedirect.com/science/article/B6TF4-4V34D9T-1/2/40a8fb895c58c4625f1238a81155b47d

Abstract: An organically modified silicate (ORMOSIL) SPME stationary phase molecularly imprinted with BDE-209 has been successfully fabricated by conventional sol-gel technique from phenyltrimethoxysilane and tetraethoxysilane. The thickness of the ORMOSIL-SPME stationary phase, on fused-silica optical fibres, was measured to be ca. 9.5μm with a volume of ca. 0.12μL. Rebinding assays and Scatchard analysis revealed that the imprinted ORMOSIL-SPME stationary phase possessed a binding affinity, KB, of 7.31.7+1010M-1 for BDE-209, with a receptor site density, Bmax, of 1.2+10-3pmol per SPME device. Besides its molecular template, the ORMOSIL-SPME stationary phase also showed good affinity (logKB>=9.5) for smaller BDE congeners commonly found in the natural environment. The density of receptor sites within the imprinted matrix for those smaller BDE congeners was even higher than that for BDE-209. This may be attributable to the binding site heterogeneity of the imprinting process that creates deformed binding sites that are suitable for the accommodation of the smaller BDE congeners. Compared to the commercially available polyacrylate and polydimethylsiloxane SPME stationary phases, the imprinted ORMOSIL-SPME devices showed much higher pre-concentration ability towards polybrominated diphenyl ethers (PBDEs), even in direct immersion sampling at room temperature. Coupled with GC-NCI-MS and GC-μECD, the imprinted ORMOSIL-SPME device was able to achieve detection sensitivity of 0.2-3.6pgmL-1 and 1-8.8pgmL-1, respectively, for commonly occurring BDE congeners, including medium to high molecular weight PBDEs. The imprinted ORMOSIL-SPME device has been successfully applied to monitor PBDE contents in municipal wastewaters
Template and target information: polybrominated diphenyl ethers, BDE-209, BDE congeners
Author keywords: molecular imprinting, Organically modified silicate, solid-phase microextraction, Polybrominated diphenyl ether determination, natural waters, Municipal wastewaters

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