MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Jiang TH, Zhao LX, Chu BL, Feng QH, Yan W, Lin JM
Article Title: Molecularly imprinted solid-phase extraction for the selective determination of 17β-estradiol in fishery samples with high performance liquid chromatography.
Publication date: 2009
Journal: Talanta
Volume: 78
Issue: (2)
Page numbers: 442-447.
DOI: 10.1016/j.talanta.2008.11.047
Alternative URL: http://www.sciencedirect.com/science/article/B6THP-4V3SY3T-1/2/6587897a328dc820e0029e8323d9548e

Abstract: A molecularly imprinted polymer (MIP) has been synthesized by a thermo-polymerization method using methacrylic acid (MAA) as functional monomer, ethylene glycol dimethacrylate (EGDMA) as cross-linker, acetonitrile as porogenic solvent, and 17β-estradiol as template. The MIP showed obvious affinity for 17β-estradiol in acetonitrile solution, which was confirmed by absorption experiments. After optimization of molecularly imprinted solid-phase extraction (MISPE) conditions, three structurally related estrogenic compounds (17β-estradiol, estriol, and diethylstilbestrol) were used to evaluate the selectivity of the MIP cartridges. The MIP cartridges exhibited highly selectivity for E2, the recoveries were 84.86.53% for MIPs and 19.11.93% for non-imprinted polymer (NIP) cartridges. The detection and quantification limits correspond to 0.023 and 0.076mgL-1. Furthermore, the MISPE methods were used to selectively extract E2 from fish and prawn tissue prior to HPLC analysis. This MISPE-HPLC procedure could eliminate all matrix interference simultaneously and had good recoveries (78.3-84.5%)
Template and target information: 17β-estradiol
Author keywords: 17β-estradiol, molecularly imprinted polymer, Solid-phase extraction, high performance liquid chromatography

  SMI logo shirt  Periodic table Genius shirt    mug featuring the template Estradiol

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner