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Reference type: Journal
Authors: Kempe M
Article Title: Oxytocin receptor mimetics prepared by molecular imprinting.
Publication date: 2000
Journal: Letters In Peptide Science
Volume: 7
Issue: (1)
Page numbers: 27-33.
DOI: 10.1023/A:1008919213207

Abstract: Oxytocin receptor mimetics were prepared by molecular imprinting using Z-oxytocin as the template. Comparative binding studies with reference polymers showed that the imprinted polymers recognized both Z-oxytocin and unprotected oxytocin selectively. The dissociation constants were 47 mu M and 102 mu M, respectively, and the density of binding sites was 12 mu mol/g. The synthetic oxytocin receptors were easily prepared, possessed high mechanical and chemical stability, and were reused without loss of selectivity and capacity after regeneration by extraction


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