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Reference type: Journal
Authors: Kugimiya A, Kohara K
Article Title: Biomimetic sensor for cAMP using an ion-sensitive field-effect transistor.
Publication date: 2009
Journal: Materials Science and Engineering: C
Volume: 29
Issue: (3)
Page numbers: 959-962.
DOI: 10.1016/j.msec.2008.09.001
Alternative URL: http://www.sciencedirect.com/science/article/B6TXG-4TCYCFB-2/2/6832605001d23f64a84272bfabc72dda

Abstract: A biomimetic sensor for cAMP was fabricated in combination with an ion-sensitive field-effect transistor (ISFET) as a transducer and a cAMP-imprinted polymer as a molecular recognition material. The cAMP-imprinted polymer was prepared using 1-allyl-2-thiourea as a functional monomer, and the binding ability and the selectivity of the polymer were evaluated. In addition, the imprinted polymer membrane was coated on the ISFET electrode, and the response of the sensor was evaluated. The cAMP-imprinted polymer showed high binding ability to and selectivity for cAMP in aqueous media. The linear relationship was obtained from 0.1 to 1.0ámM cAMP from the calibration curve in the cAMP-sensor
Template and target information: cAMP
Author keywords: molecular imprinting, cAMP, Thiourea group, molecular recognition, Ion-sensitive field-effect transistor


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