Authors: Lachová M
, Lehotay J
, Skacáni I
, Cizmárik A
Molecularly Imprinted Solid-Phase Extraction of 1-Methyl-2-piperidinoethylesters of Alkoxyphenylcarbamic Acid from Human Plasma, Comparison with Classical Solid-Phase Extraction.
Publication date: 2009
Journal: Journal of Liquid Chromatography & Related Technologies
Alternative URL: http://www.informaworld.com/10.1080/10826070903187684
Abstract: Molecularly imprinted polymers for 1-methyl-2-piperidinoethylester of 2-methoxyphenylcarbamic acid (template) have been synthesised using a non-covalent imprinting approach. Acrylamid and methacrylic acid, respectively, were used as the functional monomers. Imprinted polymers were used as the sorbents for solid-phase extraction (MISPE). The capacity and selectivity of prepared imprinted polymers was investigated. The non-imprinted (blank) polymers were prepared by the same way without template to study the non-specific interactions. Molecularly imprinted polymer prepared from methacrylic acid was used to preconcentrate 1-methyl-2-piperidinoethylester of 2-methoxyphenylcarbamic acid and its analogues from spiked human plasma
Template and target information: 1-methyl-2-piperidinoethylester of 2-methoxyphenylcarbamic acid
Author keywords: HPLC, molecularly imprinted polymer, SPE
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