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Reference type: Journal
Authors: Sousa MD, Barbosa CM
Article Title: Molecularly imprinted polymers for controlling drug release. Part 1: Synthesis and characterization.
Publication date: 2009
Journal: Quimica Nova
Volume: 32
Issue: (6)
Page numbers: 1609-1619.
DOI: 10.1590/S0100-40422009000600045
Alternative URL: http://www.scielo.br/pdf/qn/v32n6/45.pdf

Abstract: Molecularly imprinted polymers (MIPs) consist of synthetic macromolecular matrix, obtained through molecular imprinting-based methods that show ability to selectively recognize important biological molecules and its application in the drug delivery field is under development. In the present review the main aspects related to the synthesis and characterization of MIPs are studied. The fundamental variables participating in the synthesis process, such as template molecule, functional monomers, cross-linking agents, solvents and imprinting approaches are discussed. Moreover, the main available methods for MIPs chemical and morphological characterization are presented and the importance of the obtained information is discussed
Author keywords: molecularly imprinted polymers (MIPs), Imprinting approaches, MIPs characterization


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