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Reference type: Journal
Authors: Dima SO, Dobre T, Sārbu A, Ghiurea M, Bradu C
Article Title: Proofs for molecular imprinting of an acrylic copolymer by phase inversion.
Publication date: 2009
Journal: UPB Scientific Bulletin, Series B: Chemistry and Materials Science
Volume: 71
Issue: (4)
Page numbers: 21-30.
Alternative URL: http://www.scientificbulletin.upb.ro/rev_docs/arhiva/full3936.pdf

Abstract: The molecular imprinting with diosgenin by phase inversion of some acrylic copolymer pearls was proved both by analyzing the liquid phase (the extracts) and the solid phase (the pearls). For this purpose, the pearls at different stages of treatment were dissolved in dimethylformamide (DMF) and analyzed by liquid chromatography method (HPLC), working with an Agilent Technologies 1200 instrument with refractive index detector (RID). Signals were obtained for the copolymer, for diosgenin and also for cholesterol, a compound from the same class as diosgenin. The cholesterol was used to demonstrate the selectivity of the new materials towards the template molecule
Template and target information: diosgenin
Author keywords: Bioactive substances, imprinted polymer, molecular recognition, phase inversion, solid phase extraction


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