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Reference type: Journal
Authors: Divya MP, Rajput YS, Sharma R
Article Title: Synthesis and Application of Tetracycline Imprinted Polymer.
Publication date: 2010
Journal: Analytical Letters
Volume: 43
Issue: (6)
Page numbers: 919-928.
DOI: 10.1080/00032710903491039
Alternative URL: https://www.researchgate.net/publication/244601818_Synthesis_and_Application_of_Tetracycline_Imprinted_Polymer

Abstract: Molecular imprinted polymer was synthesized by polymerization of methacrylate and ethylene glycol dimethacrylate in presence of tetracycline. The prepared polymer exhibited selectivity of 1.8 to 3.9 over non-imprinted polymer depending on nature of solvent. In water, 3.45 mg of tetracycline bind to 1 g of imprinted polymer. Non-covalent interactions between tetracycline and polymer provided selectivity to imprinted polymer. The polymer was evaluated in column chromatography and the bound tetracycline can be eluted with acetonitrile. Ciprofloxacin interacted with imprinted polymer, whereas amoxicillin did not. The feasibility of using MIP for concentrating tetracycline from milk has been demonstrated
Template and target information: tetracycline
Author keywords: milk, molecular imprinting, non-covalent imprinting, stationary phase, Tetracycline

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