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Reference type: Journal
Authors: Hu J, Mao XM, Cao SS, Yuan XH
Article Title: Recognition of proteins and peptides: Rational development of molecular imprinting technology.
Publication date: 2010
Journal: Polymer Science Series A
Volume: 52
Issue: (3)
Page numbers: 328-339.
DOI: 10.1134/S0965545X10030156

Abstract: Abstract: The creation of tailor-made receptors which are able to recognize molecular targets with high affinity and selectivity has attracted much attention in the field of chemistry, physics, and biology. Molecular imprinting has proved to be an effective technique for generating specific recognition sites in synthetic polymers. The synthesis of molecular imprinted polymers specific for proteins and peptides has been a focus for many scientists working in the area of molecular recognition, since the creation of synthetic polymers that can specifically recognize biomacromolecules is a very challenging but potentially extremely rewarding work. These polymers with specificity for biological macromolecules have considerable potential for applications in the areas of solid phase extraction, catalysis, medicine, clinical analysis, drug delivery, environmental monitoring, and sensors. In this review, the authors discuss the developed approaches associated with the imprinting of peptides and proteins, and provide an overview of the significant progress achieved within this field. Finally, the possible mechanism of the molecular imprinting and recognition has been discussed
Template and target information: Review - MIPs for peptides and proteins

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