Editors: Cullum BM, Porterfield DM, Booksh KS
City: Orlando, Florida, USA
ISBN: 0277-786X ISSN: 16057422 ISBN: 978-081948138-2
Volume number: 7674
Conference information: Smart Biomedical and Physiological Sensor Technologies VII
Abstract: A surface plasmon resonance (SPR) sensor to quantify glucose using a molecularly imprinted polymer was developed. The polymer was prepared by crosslinking poly(allylamine) in the presence of glucose phosphate, monobarium salt (GPS-Ba) and attached to a thin film of gold (50 nm) which had been sputtered on top of a glass slide, via amide coupling. Upon removal of the template, this sensor was used to detect glucose in human urine in physiologically significant levels (1-20 mg/ml). Signal enhancement of the glucose sensor was made possible by incorporating gold nanoparticles in the polymer.
Template and target information: glucose phosphate, monobarium salt, GPS-Ba, glucose
Author keywords: surface plasmon resonance, molecular imprinting, biomimetic sensor, hydrogels, glucose