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Reference type: Journal
Authors: Sun T, Li YY, Zhang HC, Hao AY
Article Title: Molecular Imprinting Technology Based on Cyclodextrins.
Publication date: 2010
Journal: Progress In Chemistry
Volume: 22
Issue: (5)
Page numbers: 888-897.
Alternative URL: http://www.progchem.ac.cn/EN/abstract/abstract10317.shtml

Abstract: Molecular imprinting technology, as an interdisciplinary field which developed recently, is applied widely in many areas. Cyclodextrins are cyclic oligosaccharides, and have proper rigidity and flexibility, excellent mechanical stability and biocompatibility. Cyclodextrins have the ability to form inclusion complexes with a wide range of substrates for their particular structures, which makes cyclodextrins as good choice of materials in molecular imprinting technology. Composing of the advantages of supramolecular chemistry, macromolecular chemistry and analytical chemistry, molecular imprinting technology based on cyclodextrins is of great guiding significance for the synthesis of artificially controlled host molecules in supramolecular chemistry and the realization of artificial enzyme with multi-recognition sites. Here, the recent development of molecular imprinting technology based on cyclodextrins is reviewed. Firstly, the synthesis of different kinds of products of molecular imprinting technology is introduced, including the synthesis clues, approaches, methods and the recognition mechanism. Then, the applications of the system in the fields of molecular recognition, chromatographic separation, electrochemical sensors and biological control are emphatically described. At last, the disadvantages in recent study and prospects are pointed out
Template and target information: Review - MIPs from cyclodextrins
Author keywords: cyclodextrin, molecular imprinting technology, cyclodextrin polymer, molecular recognition


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