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Reference type: Conference Proceeding
Authors: Liu Z, Bucknall DG, Allen MG
Publication date: 2009
Article title: Recognition and absorption of the water-soluble X-ray contrast medium iodixanol using molecularly imprinted polymers for biomedical applications.
Page numbers: 39-44

Volume number: 1138
Conference information: Materials Research Society Symposium Proceedings

Abstract: This work presents the study on the recognition and absorption of the water-soluble X-ray contrast medium iodixanol in aqueous solution using synthetic molecularly imprinted polymers (MIPs). A non-covalent imprinting technique was applied to prepare iodixanol-imprinted polymers using 4-vinylpyridine as the functional monomer and ethylene glycol dimethacrylate as the cross-linker. The effects of quantity of iodixanol templates, the crosslink density, and the solvent were studied in terms of the binding capacity and imprint effect of the polymers. UV-vis spectrometric analysis shows that the highest binding capacity achieved is 284 mg iodixanol per gram of dry polymer, which is 8.8 times higher than the binding capacity of the non-imprinted control polymers (NIPs). SEM and BET surface analysis have also been performed to investigate the effect of morphology and porosity on the binding capacities of polymers. - 2009 Materials Research Society
Template and target information: iodixanol

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