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Reference type: Journal
Authors: Buszewski B, Ricanyová J, Gadzala-Kopciuch R, Szumski M
Article Title: Supramolecular recognition of estrogens via molecularly imprinted polymers.
Publication date: 2010
Journal: Analytical and Bioanalytical Chemistry
Volume: 397
Issue: (7)
Page numbers: 2977-2986.
DOI: 10.1007/s00216-010-3859-5
Alternative URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906748/

Abstract: Abstract: The isolation and preconcentration of estrogens from new types of biological samples (acellular and protein-free simulated body fluid) by molecularly imprinted solid-phase extraction has been described. In this technique, supramolecular receptors, namely molecularly imprinted polymers (MIPs) are used as a sorbent material. The recognition sites of MIPs were prepared by non-covalent multiple interactions and formed with the target 17β-estradiol as a template molecule. High-performance liquid chromatography with spectroscopic UV, selective, and a sensitive electrochemical CoulArray detector was used for the determination of 17β-estradiol, estrone, and estriol in simulated body fluid which mimicked human plasma
Template and target information: 17β-estradiol, estrone, estriol
Author keywords: estrogens, MIPs, SPE, HPLC-UV, EC

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