MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Lei JD, Tan TW
Article Title: Chiral separation of ketoprofen and thermodynamic study in molecular imprinting.
Publication date: 2002
Journal: Acta Chimica Sinica
Volume: 60
Issue: (7)
Page numbers: 1279-1283.
Alternative URL: http://sioc-journal.cn/Jwk_hxxb/EN/abstract/abstract326553.shtml

Abstract: A chiral stationary phase for the enantioselective separation of ketoprofen has been prepared by molecular imprinting, in which 4-vinylpyridine (functional monomer) and ethylene glycol dimethacrylate were copolymerised in the presence of (S)- ketoprofen. Racemic ketoprofen was efficiently resolved on the molecular imprinting polymer. Capacity factor (k(s)') of (S)- ketoprofen and separation factor (alpha) were 9.52 and 1.52, respectively. Furthermore, the polymer was able to separate ketoprofen from the structurally related ibuprofen and naproxen. Effects of concentration of acetic acid in the mobile phase, flow rate and temperature were studied. The change of enthalpy and entropy were estimated. It was found that enantioselective separation was enthalpy controlled
Template and target information: ketoprofen


  Periodic table Vindaloo - the chemical formula for curry shirt  Periodic table Bag bag  Meerkat somebody mention coffee mug

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner