MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Zhang Y, Dong XC
Article Title: Evaluation of Enrofloxacin Imprinted Polymeric Microspheres Synthesized with Living/Controlled Radical Polymerization.
Publication date: 2008
Journal: Journal of Instrumental Analysis
Volume: 27
Issue: (10)
Page numbers: 1025-1030.
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTOTAL-TEST200810002.htm

Abstract: The method of using one living/controlled radical polymerization(reversible addition-fragmentation chain transfer radical polymerization,RAFT ploymerization) for the sythesis of molecularly imprinted microsphere was developed.Combined with the precipitation polymerization,the MIP microspheres were prepared using acetonitrile as the dispersant,enrofloxacin as the template molecule,methyacrylic acid(MAA) as the functional monomer,ethylene dimethacrylate(EDMA) as the crosslinker,cumyl dithiobenzoate (CDB) as the RAFT agent and azobisisobutyronitrile(AIBN) as the initiation agent.The effects of the reaction conditions including the temperature and monomer concentration on the preparation were studied.The diameter and dispersity of MIP micropheres could be controlled through the ratio of AIBN and CDB.The results of scanning electron microscopic images showed that better particle size distribution of MIP microspheres with a diameter range of 2.0-2.2 μm was obtained.The equilibrium adsorption experiment showed that the binding ability of MIP for the template molecule was superior to that of non-imprinted polymer.The amount of saturation adsorption for enrofloxacin and lomefloxacin were 37.3 and 19.5 μmol·g-1,respectively,indicating that the MIP microspheres could well recognize the template molecule.
Template and target information: enrofloxacin
Author keywords: molecularly imprinted polymeric microsphere, living, controlled radical polymerization, Reversible addition-fragmentation chain transfer polymerization, Enrofloxacin, precipitation polymerization

  Mister Benzene Get Well Soon card  Chemistry peptide mug  Beach bunny periodic table shirt

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner