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Reference type: Journal
Authors: Ochi Y, Matsui J, Tamaki K, Miyoshi D, Sugimoto N
Article Title: New Central Dogma in Molecular Ecology. (22): Molecular imprinting utilizing water-soluble poly(methacrylic acid) derivatives for recognition of biologically active compounds.
Publication date: 2002
Journal: Nippon Kagakkai Koen Yokoshu
Volume: 81
Issue: (2)
Page numbers: 864.
Alternative URL: http://sciencelinks.jp/j-east/display.php?id=000020022002A0457368

Abstract: We recently reported on a molecular imprinting technique for synthesizing substrate-selective polymers, whereby linear polymers having polymerizable and functional pendants are cross-linked in the presence of template species. In this study, we prepared water-soluble linear polymers by partial modification of poly(methacrylic acid) with 4-vinylbenzyl chloride by DBU method. Using the linear polymers, synthesis of substrate-selective polymers was performed in several polar solvents. We will report the affinity and selectivity of resultant cross-linked polymers to biologically active compounds. The effects of solvents on the performance of the imprinted polymers will be also discussed. (author abst.)

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