Abstract: Macromolecularly imprinted calcium phosphate/alginate (CP/CA) hybrid polymermicrospheres were prepared from sodium alginate and ammonium monohydric phosphate by using calcium chloride as gelling agent in phase-inverse suspension. The CP/CA hybrid polymer microspheres have better spherical morphology, transparence and mechanical intensity in wet hydrogel. The results of rebinding behavior measure showed that there was an obvious improvement in therebinding capacity. The resultsofinfrared spectrum analysis demonstrated that newhybridcomponents were produced in these calcium alginate/phosphate hybrid polymer microspheres and this matrix indeed could be used as a new matrix for protein macromolecular imprinting.
Template and target information: protein
Author keywords: macromolecularly imprinted polymer microspheres, calcium phosphate, alginate hybrid polymer micro-spheres, sodium alginate, ammonium monohydric phosphate, Bovine serum albumin, Hybrid