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Reference type: Conference Proceeding
Authors: Hong CC, Lin CC, Hong CL, Chang PH
Publication date: 2011
Article title: Low cost and high specific anesthetic biosensors with functionally imprinted nanocavities on polymer films.
Page numbers: 1196-1199
DOI: 10.1109/TRANSDUCERS.2011.5969326

ISBN: Pending
Conference information: Proceedings of the 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference (TRANSDUCERS),

Abstract: This paper presents low cost and high specific anesthetic biosensors with functionally imprinted nanocavities on polymer films. Propofol (2, 6-di-isopropylphenol) is an intravenous anesthetic, widely used in induction of anesthesia, total intravenous anesthesia and sedation of intensive care unit patients. Although the propofol concentration in blood can be detected by high-performance liquid chromatography and/or gas chromatography, these methods are time-consuming and not ease of access. In this work, we control the morphology of imprinted nanocavities on molecularly imprinted biosensors by adjusting polymer composition. Our developed biosensors have been compared with a conventional spectrophotometer to investigate surface morphology and performance of the anesthetic biosensors. The performance of the anesthetic biosensors can be enhanced by adjusting morphology of imprinted nanocavities. The newly developed biosensors have been characterized using our developed optofluidic microsystem
Template and target information: Propofol, 2,6-di-isopropylphenol
Author keywords: anesthetic propofol, Biosensors, microfluidic biochips, Molecularly imprinted polymers


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