Authors: Jiao FP
, Huang KL
, Yu JG
, Peng XH
, Zhao XH
, Ning FR
Study on Process of Thermodynamics for Chiral Separation of Naproxen in Molecular Imprinting.
Publication date: 2005
Journal: Materials Review
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTotal-CLDB200508032.htm
Abstract: A chiral stationary phase for the enantioselective separation of naproxen can be prepared by molecular imprinting,in which 4-vinylpyridine(functional monomer)and trimethylol propane trimethacrylate are copolymerized in the presence of S-naproxen.Racemic naproxen is efficiently resolved on the molecular imprinting polymer. Furthermore,different functional monomers,flow rate in the mobile phase,temperature of column are investigated.The thermodynamic parameters are estimated, it is found that enantioselective separation is enthalpy controlled.
Template and target information: S-naproxen, naproxen
Author keywords: molecular imprinting, resolution, naproxen, thermodynamics
Join the Society for Molecular Imprinting
New items RSS feed
View latest updates
Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent
to go to the sign-up page.
Is your name elemental
? Enter your name and find out by clicking either of the buttons below!
Other products you may like: