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Reference type: Journal
Authors: Jiao FP, Huang KL, Yu JG, Peng XH, Zhao XH, Ning FR
Article Title: Study on Process of Thermodynamics for Chiral Separation of Naproxen in Molecular Imprinting.
Publication date: 2005
Journal: Materials Review
Volume: 19
Issue: (8)
Page numbers: 114-116.
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTotal-CLDB200508032.htm

Abstract: A chiral stationary phase for the enantioselective separation of naproxen can be prepared by molecular imprinting,in which 4-vinylpyridine(functional monomer)and trimethylol propane trimethacrylate are copolymerized in the presence of S-naproxen.Racemic naproxen is efficiently resolved on the molecular imprinting polymer. Furthermore,different functional monomers,flow rate in the mobile phase,temperature of column are investigated.The thermodynamic parameters are estimated, it is found that enantioselective separation is enthalpy controlled.
Template and target information: S-naproxen, naproxen
Author keywords: molecular imprinting, resolution, naproxen, thermodynamics


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