Proceedings title: Cold Spring Harbor Symposia on Quantitative Biology
Volume number: 32
I had planned to attend these meetings to listen to those who presented here new and important facts, but instead I have been invited to discuss the evolution of theories of antibody formation. It is obvious that the important discoveries of the last few years have had a great influence on our ideas about antibody formation. I would like to describe these as objectively as possible. Indeed, I may have gone too far in this respect when I said in my short abstract that the Selective Theory is now more attractive to me than it ever appeared earlier; for, some of my friends at this meeting have implored me not to abandon the template idea completely.
EHRLICH'S SELECTIVE THEORY OF PREFORMED RECEPTORS
I believe that any report on the evolution of theories of antibody formation must start with Ehrlich's ingenious side chain theory, enunciated at the end of the last...