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Reference type: Journal
Authors: Yang ZP, Yan JL, Zhang CJ
Article Title: Piezoelectric detection of bilirubin based on bilirubin-imprinted titania film electrode.
Publication date: 2012
Journal: Analytical Biochemistry
Volume: 421
Issue: (1)
Page numbers: 37-42.
DOI: 10.1016/j.ab.2011.10.027
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0003269711006932

Abstract: A novel quartz crystal microbalance (QCM) sensor with a high selectivity and sensitivity has been developed for bilirubin determination, based on the modification of bilirubin-imprinted titania film onto a quartz crystal by molecular imprinting and surface sol-gel techniques. The performance of the developed bilirubin biosensor was evaluated and the results indicated that a sensitive bilirubin biosensor could be fabricated. The obtained bilirubin biosensor presents high-selectivity monitoring of bilirubin, better reproducibility, shorter response time (30 min), wider linear range (0.1 - 50 μM), and lower detection limit (0.05 μM). The analytical application of the bilirubin biosensor confirms the feasibility of bilirubin determination in serum sample
Template and target information: bilirubin
Author keywords: Bilirubin, QCM, Bilirubin-imprinted titania film, detection


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