Publisher: IACSIT Press
Volume number: 25
Conference information: Proceedings of the 2011 International Conference on Nanotechnology and Biosensors
Abstract: A novel molecular imprinted polymer (MIP) based electrode has been investigated for electrochemical impedimetric detection of creatinine. Magnitude of impedance was measured in a frequency range of 10 mHz to 60 KHz in the presence and absence of creatinine. Based on the best-fitting equivalence circuit analysis, it was found that the charge-transfer impedance of the electrode increased by the addition of creatinine and increased further with increasing concentrations. Control experiments with non-imprinted polymer (NIP) electrode showed that the sensor is totally non-responsive to creatinine. The low-detectionlimit of the impedance sensor is 50 ng/mL. The sensor surface of the fabricated MIP electrode is easily renewable for repeated cyclic use in multiple analyses.
Template and target information: creatinine
Author keywords: electrochemical impedance, Creatinine sensor, Raman spectroscopy, Molecular Imprinted Material, biosensor, label-free detection