MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Olsson GD, Karlsson BCG, Shoravi S, Wiklander JG, Nicholls IA
Article Title: Mechanisms underlying molecularly imprinted polymer molecular memory and the role of crosslinker: resolving debate on the nature of template recognition in phenylalanine anilide imprinted polymers.
Publication date: 2012
Journal: Journal of Molecular Recognition
Volume: 25
Issue: (2)
Page numbers: 69-73.
DOI: 10.1002/jmr.2147

Abstract: A series of molecular dynamics simulations of prepolymerization mixtures for phenylalanine anilide imprinted co-(ethylene glycol dimethacrylate-methacrylic acid) molecularly imprinted polymers have been employed to investigate the mechanistic basis for template selective recognition in these systems. This has provided new insights on the mechanisms underlying template recognition, in particular the significant role played by the crosslinking agent. Importantly, the study supports the occurrence of template self-association events that allows us to resolve debate between the two previously proposed models used to explain this system's underlying recognition mechanisms. Moreover, the complexity of the molecular level events underlying template complexation is highlighted by this study, a factor that should be considered in rational molecularly imprinted polymer design, especially with respect to recognition site heterogeneity. Copyright 2012 John Wiley & Sons, Ltd
Template and target information: phenylalanine anilide
Author keywords: molecularly imprinted polymer, MIP, Molecular dynamics, molecular recognition, phenylalanine anilide


  Mister Benzene and Mister Cyloheptatetraene shirt  Mug featuring the name Ian spelled out in the single letter amino acid code    Shirt featuring the template Phenylalanine anilide

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner