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Reference type: Conference Proceeding
Authors: Li HX, Wei QQ, Liu YY, Wu K
Publication date: 2012
Article title: Cholesterol Detection by Self-Assembled Dodecyl Thiol Layers Extracted Cholesterol on the Ce-Sb Codoped SnO2 Film Electrodes.
Page numbers: 198-203
DOI: 10.4028/www.scientific.net/AMR.465.198 Alternative URL: http://www.scientific.net/AMR.465.198

Proceedings title: Advanced Materials Research
Editors: Cong HL
Publisher: Trans Tech Publications
City: Switzerland
Volume number: 465
Conference information: Advanced in Nanoscience and Technology

Abstract: Cerium (Ce) and antimony (Sb) codoped tin dioxide (SnO2) films (Ce:Sb:Sn=2:3:95 molar ratio) have been prepared on the surface of titanium (Ti) substrate by sol-gel method. A self-assembled layer (SAL) of dodecyl thiol with cholesterol was formed on the surface of Ce-Sb codoped SnO2 films/Ti electrode. The SAL was then used with the cholesterol as the template forming the molecular imprinting layer. The extraction of cholesterol has resulted in formation of sites in the layer of dodecyl thiol which could have been used as channels for the ferro-ferric cyanide coupled redox reaction to quantify recombining cholesterol on the sites. This sensor prototype could detect cholesterol concentrations between 40 and 60 μM. X-ray diffraction (XRD) and scanning electron microscopy (SEM) have been used to analyze the structure and morphology of the samples.
Template and target information: cholesterol
Author keywords: cholesterol, self-assembled layer, sol-gel, tin dioxide


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