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Reference type: Book Chapter
Authors: Moreno-Bondi MC, Benito-Peņa ME, Urraca JL, Orellana G
Publication date: 2012
Chapter title: Immuno-Like Assays and Biomimetic Microchips.
Page numbers: 111-164.
DOI: 10.1007/128_2010_94

Book title: Molecular Imprinting
Editors: Haupt K
Publisher: Springer
City: Berlin / Heidelberg
ISBN: 978-3-642-28420-5
Series title: Topics in Current Chemistry
Volume number: 325

Abstract: Biomimetic assays with molecularly imprinted polymers (MIPs) are bound to be an alternative to the traditional immuno-analytical methods based on antibodies. This is due to the unique combination of advantages displayed by the artificial materials including the absence of animal inoculation and sacrifice, unnecessary hapten conjugation to a carrier protein for stimulated production, the possibility of manufacturing MIPs against toxic substances, excellent physicochemical stability, reusability, ease of storage, and recognition in organic media. If the selectivity and affinity of MIPs are increased, many more immuno-like assays will be developed using radioactive, enzymatic, colorimetric, fluorescent, chemiluminescent, or electrochemical interrogation methods. This chapter provides a comprehensive comparison between the bio- and biomimetic entities and their usage
Template and target information: Review - MIPs in assays and microchips
Author keywords: Biomimetic assay, Immuno-like assay, Microchip, molecularly imprinted polymer

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