MIPs logo MIPdatabase      Special issue call for papers   
Custom Search
Reference type: Journal
Authors: Gao YB, Zhu GF, Fan J
Article Title: Study on the synthesis and characteristics of levofloxacin molecularly imprinted polymer microsphere.
Publication date: 2011
Journal: Chemical Research and Application
Volume: 23
Issue: (8)
Page numbers: 980-984.
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTOTAL-HXYJ201108004.htm

Abstract: A molecularly imprinted polymer(MIP)microsphere using levofloxacin as template molecule,MAA as function monomer,EDMA as cross-linking agent was synthesized via precipitation polymerization.The surface morphologies and characteristics of the microsphere were characterized by infrared spectroscopy and scanning electron microscopy.The adsorption properties and selective adsorption capacity of polymer microsphere for the template and the anologues were determined by the static adsorption equilibrium experiments and the Scatchard analysis.The results showed that the adsorption was fast and the adsorption equilibrium was achieved in 40 min.The adsorption process of MIP upon template could be described by a pseudo-second-order kinetics.There were two kinds of binding sites in the MIP and the dissociation constants were 0.672 mmol/L and 1.541 mmol/L,respectively.The maximum adsorption capacities of the two kinds of binding sites were 313 μmol/g and 378 μmol/g,respectively.Compared with the corresponding non-imprinted polymer,MIP exhibited better adsorption properties and selectivity for the template and the anologues.
Template and target information: levofloxacin

  Mister Benzene and Mister Cyloheptatetraene shirt  Chemistry peptide mug  Beach bunny periodic table shirt


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner