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Reference type: Conference Proceeding
Authors: Xu W, Li X, Zhang WY, Ying XG
Publication date: 2012
Article title: Electrochemical Sensors for L-Tryptophan Based on Molecularly Imprinted Polymers.
Page numbers: 434-438
DOI: 10.4028/www.scientific.net/AMR.499.434 Alternative URL: http://www.scientific.net/AMR.499.434

Proceedings title: Advanced Materials Research
Editors: Mao HK, Aggarwal D, Lee MH, Liu HF, Zhao MT
Publisher: Trans Tech Publications
City: Switzerland
Volume number: 499
Conference information: Polymer Composites and Polymer Testing

Abstract: A novel sensing element for direct detection of L-Tryptophan (L-Trp) in human serum was proposed by combination of electrochemical transduction and molecular imprinting technique. The sensing element was prepared by electropolymerization of o-phenylenediamine (o-PD) on the gold electrode in the presence of template L-Trp. The electrochemical property of the sensor was characterized by differential pulse voltammetry (DPV). The linear response range of the sensor for L-Trp concentration was 110-8 mol/L~2110-8 mol/L with a detection limit of 0.310-8 mol/L. The results show that this approach has the potential to generate a universal inexpensive assay methodology of high sensitivity, specificity and simplicity to detect L-Trp.
Template and target information: L-Tryptophan, L-Trp
Author keywords: Electrochemical sensor, electropolymerization, L-tryptophan, molecular imprinting, o-phenylenediamine


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