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Reference type: Journal
Authors: Madhuri R, Tiwari MP, Kumar D, Mukharji A, Prasad BB
Article Title: Biomimetic piezoelectric quartz sensor for folic acid based on a molecular imprinting technology.
Publication date: 2011
Journal: Advanced Materials Letters
Volume: 2
Issue: (4)
Page numbers: 264-267.
DOI: 10.5185/amlett.indias.194

Abstract: A novel molecularly imprinted polymer (MIP)-modified quartz crystal microbalance (QCM) sensor with high selectivity has been developed for the determination of folic acid via activator generated-atom transfer radical polymerization (AGET-ATRP) technique. It requires an alkyl halide (R-X) as an initiator, a transition metal complex as a catalyst, and an amine as reducing agent. Herein, chlorosilane was used as initiator which was grafted onto the self assembled monolayer modified-quartz crystal surface followed by the addition of pre-polymer mixture which latter underwent thermal cross-linking resulting in MIP-modified QCM sensor. The linear working range (quantification) was found to be 0.6-26.0 μg L-1, with the detection limit as low as 0.08 μg L-1 (S/N=3). Copyright 2011 VBRI press.
Template and target information: folic acid
Author keywords: molecularly imprinted polymer, quartz crystal microbalance, Folic acid, activator generated-atom transfer radical polymerization

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