Authors: Haginaka J
, Miura C
, Funaya N
, Matsunaga H
Monodispersed Molecularly Imprinted Polymer for Creatinine by Modified Precipitation Polymerization.
Publication date: 2012
Journal: Analytical Sciences
Alternative URL: http://www.jstage.jst.go.jp/article/analsci/28/4/28_315/_article
Abstract: A monodispersed molecularly imprinted polymer (MIP) for creatinine was prepared by modified precipitation polymerization. The retention and molecular-recognition properties of the prepared MIP were evaluated by the hydrophilic interaction chromatography mode using a mixture of ammonium acetate buffer and acetonitrile as a mobile phase in liquid chromatography. The MIP had a specific recognition ability for creatinine, while other structurally related compounds, such as hydantoin, 1-methylhydantoin, 2-pyrrolidone, N-hydroxysuccinimide and creatine, could not be recognized on the MIP. In addition to shape recognition, hydrophilic interactions could work for the recognition of creatinine on the MIP.
Template and target information: creatinine
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