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Reference type: Journal
Authors: Gupta H, Aqil M
Article Title: Contact lenses in ocular therapeutics.
Publication date: 2012
Journal: Drug Discovery Today
Volume: 17
Issue: (9-10)
Page numbers: 522-527.
DOI: 10.1016/j.drudis.2012.01.014
Alternative URL: http://www.sciencedirect.com/science/article/pii/S1359644612000323

Abstract: Drug delivery is a difficult task in the field of ocular therapeutics. Owing to the physiological and anatomical constraints of the eye, it is difficult to obtain the correct therapeutic concentration of a drug at the required site of action. This has led to clinicians recommending frequent dosing, which has resulted in noncompliance by patients and decreased cost effectiveness. To overcome these barriers, scientists have explored novel ocular delivery systems, such as in situ gels, ocuserts, nanoparticles and liposomes. A particularly novel form of such a delivery system are contact lenses, which are thin, curved plastic disks that are designed to cover the cornea and which cling to the surface of the eye owing to surface tension. In this article, we describe the introductory literature on ocular delivery using contact lenses, their classification and manufacturing process, and recent advances on drug delivery techniques using such lenses
Template and target information: Review - contact lenses in ocular delivery


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