MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Xin Y, Tong YJ, Yang HL, Zhang L, Zhang YR, Chen Y, Wang W
Article Title: Study on the Glutathione Molecularly Imprinted Polymers with Different Functional Monomers.
Publication date: 2012
Journal: Acta Chimica Sinica
Volume: 70
Issue: (6)
Page numbers: 803-811.

Abstract: Using glutathione (GSH) as template molecule, acrylamide (AM) and methacrylic acid (MAA) as functional monomer, different glutathione-molecularly imprinted polymers (GSH-MIPs) were developed and synthesized with molecularly imprinted technique. The effects for adsorption capacity, including molar ratio of template molecule-functional monomer, pH of loading buffer, adsorption equilibrium time and loading concentration were discussed in detail. The result demonstrated that the polymers with raw material mole ratios at 1 : 5 for GSH : AM, and 1 : 4 for GSH : MAA showed higher adsorption capacity, the optimal pH values for the adsorption of GSH-MIPAMs and GSH-MIPMAAs to GSH were 3.0 and 5.0, respectively; furthermore, the optimal GSH loading concentrations were 1.50 similar to 2.00 g/L for GSH-MIPAMs, and 1.00 similar to 1.50 g/L for GSH-MIPMAAs; additionally, the adsorption equilibrium time was 20 h for GSH-MIPAMs and 18 h for GSH-MIPMAAs. In addition, the binding of GSH analogues were also applied to the synthesized poly-mers, and the results reflected that GSH-MIPs showed low recognition to these analogues. This protocol was further employed for the extraction and separation of GSH from yeast cells samples. The extraction recoveries of GSH-MIPAMs and GSH-MIPMAAs were 41% and 77%, respectively, it was of great potential in the purification of GSH
Template and target information: glutathione, GSH
Author keywords: molecularly imprinting, Glutathione, GSH-MIPs, Preparation, Adsorption conditions, yeast extracts, Adsorption performance

  Periodic table Soup - the chemical formula for soup apron  Periodic table Bag bag  Meerkat somebody mention coffee mug

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner