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Reference type: Journal
Authors: Liu S, Li XZ, Lei P, Hong LX
Article Title: Preparation of molecular imprinted polymer of neferine.
Publication date: 2010
Journal: Central South Pharmacy
Volume: 8
Issue: (8)
Page numbers: 575-578.
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZNYX201008006.htm

Abstract: Objective To prepare molecular imprinted polymers(MIPs)of neferine.Methods MIPs of neferine were synthesized by hot-initiated polymerization with neferine as imprinting molecules,a-methacrylic acid(a-MAA) as the functional monomer and ethylene glycol dimethacrylate(EDMA) as the cross-linker.Uniform design was used to optimize the condition.The selectivity of the prepared MIP of neferine was studied by packing it in a solid-phase extraction column.Results The optimum preparation condition was as follows:neferine 0.1 mmol,temperature 50 C,a-MAA 0.8 mmol,and EDMA 2.5 mmol.Conclusion The MIP prepared by optimum method exhibits high selectivity and good recognition ability to neferine.
Template and target information: neferine
Author keywords: Molecularly imprinted polymers, neferine, lotus plumule

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