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Reference type: Book Chapter
Authors: Poma A, Whitcombe M, Piletsky S
Publication date: 2013
Chapter title: Plastic Antibodies.
Page numbers: 105-129.
DOI: 10.1007/5346_2012_24

Book title: Designing Receptors for the Next Generation of Biosensors
Editors: Piletsky SA, Whitcombe MJ
Publisher: Springer
City: Berlin, Heidelberg
ISBN: 978-3-642-32329-4
Series title: Springer Series on Chemical Sensors and Biosensors
Volume number: 12

Abstract: Molecular recognition plays an important role in diagnostics, catalysis, separation, and drug development. For years these tasks have been entrusted to antibodies, but recently some viable alternatives are starting to emerge. This review provides a brief overview of natural and synthetic recognition systems, highlighting their advantages and drawbacks. Examples of synthetic receptors include aptamers, engineered proteins, and molecularly imprinted polymers (MIPs). The focus of the present work is on the development and application of a novel class of synthetic receptors - MIP nanoparticles (''plastic antibodies'').
Template and target information: Review - MIP nanoparticles
Author keywords: enzyme mimics, molecularly imprinted polymer, nanoparticles, sensing, separation

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