Authors: Lemau de TalancÚ V
, Massinon O
, Baati R
, Wagner A
, Vincent SP
First steps towards conformationally selective artificial lectins: the chair-boat discrimination by molecularly imprinted polymers.
Publication date: 2012
Journal: Chemical Communications
Abstract: A series of molecularly imprinted polymers (MIPs) were prepared in the presence of a synthetic galactoside locked in a 1,4B boat conformation. This study demonstrates that, depending on the polymerisation technique, an organic material can selectively bind a carbohydrate in a biologically relevant boat conformation
Template and target information: synthetic galactoside locked in a 1,4B boat conformation, 1,4-anhydro-1-deoxy-1-hydroxymethyl(4-isopropyl)phenyl-D-galactopyranose
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