MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Prasad BB, Pandey I, Srivastava A, Kumar D, Tiwari MP
Article Title: Multiwalled carbon nanotubes-based pencil graphite electrode modified with an electrosynthesized molecularly imprinted nanofilm for electrochemical sensing of methionine enantiomers.
Publication date: 2013
Journal: Sensors and Actuators B: Chemical
Volume: 176
Page numbers: 863-874.
DOI: 10.1016/j.snb.2012.09.050

Abstract: Enantioselective electrochemical nanosensors for methionine isomers, based on electropolymerized molecular imprinting approach, have been fabricated. For this, benzidine and methionine were first assembled on the surface of multiwalled carbon nanotubes-modified pencil graphite electrode with the formation of amide and subsequent electropolymerization. During the course of electropolymerization, methionine molecules were instantly oxidized to methionine sulfone as print molecules involving electrostatically driven hydrogen-bonding links in the polymer-template adduct. After template (methionine sulfone) extraction, a novel molecularly imprinted polymer film was eventually coated over the electrode surface, possessing several molecular cavities. These cavities selectively encapsulated l-methionine in its oxidized form. The modified electrode responded maximum differential pulse cathodic stripping voltammetry response at optimized operating conditions. A linearity in the current-concentration profile was observed in the wide range [11.7 - 206.3 ng mL-1 (aqueous), 11.7 - 197.4 (pharmaceutical), and 11.8 - 152.3 ng mL-1 (blood serum)] of l-methionine concentration with detection limit 2.4 - 3.0 ng mL-1 (S/N = 3). The average recovery of analyte was higher than 98.0% with RSD < 4%, without any cross-reactivity and false positives. The proposed method has also been examined for the enantioselective recognition of methionine isomers (d- and l-) quantitatively, in complicated matrices of real samples
Template and target information: l-methionine, d-methionine
Author keywords: electropolymerization, d- and l-methionine, molecularly imprinted polymer, enantioselectivity, Differential pulse cathodic stripping voltammetry


  I love MISPE mug  multi MIPs logo mug  British periodic table patriotic tote bag

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner