MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Chen DD, He DX, Qi KZ, Lu CZ
Article Title: Determination of Cefotaxime Residue in Milk by Molecular Imprinted Solid Phase Extraction/Capillary Electrophoresis.
Publication date: 2012
Journal: Journal of Instrumental Analysis
Volume: 31
Issue: (10)
Page numbers: 1334-1338.
Alternative URL: http://fxcsxb.com/ch/reader/view_abstract.aspx?file_no=20121022&flag=1

Abstract: A molecularly imprinted polymer for cefotaxime (CTX-MIP) was synthesized by the molecular imprinting technique using cefotaxime (CTX) as template molecule, α-methacrylic acid (MAA) as functional monomer, ethylene glycol dimethacrylate (EGDMA) as cross linking agent. By using the cefotaxime molecularly imprinted polymer as sorbent in solid-phase extraction column, a molecularly imprinted solid phase extraction-capillary electrophoresis (MISPE-HPCE) method was developed for the determination of cefotaxime residue in milk. The results showed that cefotaxime imprinted polymer exhibited a higher selectivity to cefotaxime compared with that of the non imprinted polymer. The linear range of cefotaxime was in the range of 0.5-100 mg/L, and the correlation coefficient was 0.9994. The recoveries at three spiked concentration levels of 10, 50, 100 mg/L were 78%, 84% and 86%, respectively, with RSDs of 3.5%-4.5%. The limit of detection (LOD, S/N=3) and the limit of quantitation (LOQ, S/N=10) were 98.52 μg/L and 329.0 μg/L, respectively. The method could meet the requirements for veterinary drug residue analysis.
Template and target information: cefotaxime, CTX
Author keywords: molecularly imprinted solid phase extraction, capillary electrophoresis, cefotaxime, milk

  Periodic table Banana Split - the chemical formula for banana split shirt  Periodic table Bag bag  Meerkat somebody mention coffee mug

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner