Conference information: Proceedings of the 5th Scientific Conference of Animal Wealth Research in the Middle East and North Africa
Abstract: A novel biomimetic potentiometric PVC polymeric membrane sensor based on a molecularly imprinted polymer was fabricated for selective recognition and determination of imidocarb dipropionate. Characteristics of the proposed biomimetic sensor containing imidocarb-methacrylic acid-ethylene glycol methacrylate were evaluated by measuring the potential response to imidocarb dipropionate in the activity range from 10-2 mmol L-1 to 10 mmol L-1 with a near Nernstian response of 28.0±0.05 mV/decade and a limit of detection of 0.0847 mmol L-1. The response time of the sensor was short (<15 s) and the membrane could be used for 4 months without any significant divergence in response. Validation of the assay method according to the quality assurance standards (range, within-day repeatability, between-day variability, standard deviation, accuracy, and good performance characteristics) was justified ensuring a reliable novel sensor for imidocarb estimation. Application of the proposed assay method for routine determination of imidocarb in pure drug and pharmaceutical formulation was verified. Samples of liver and kidney from bovine animals were analyzed to ensure their suitability for human consumption and the results compared favorably with data obtained by the unique standard method using high performance liquid chromatography.
Template and target information: imidocarb dipropionate