MIPs logo MIPdatabase      Special issue call for papers   
Custom Search
Reference type: Journal
Authors: Xie JQ, Cai CQ, Yang H, Chen XM
Article Title: Synthesis and Application of Molecularly Imprinted Polymer on Selective Solid-Phase Extraction for the Determination of Artemisinin in Artemisia Annua L.
Publication date: 2013
Journal: Analytical Letters
Volume: 46
Issue: (1)
Page numbers: 107-119.
DOI: 10.1080/00032719.2012.706851

Abstract: Molecular imprinted polymer (MIP) was prepared through thermal polymerization by using artemisinin as the template molecule, styrene as the functional monomer, ethylene glycol dimethacrylate (EGDMA) as the cross-linker, and azobisisobutyronitrile (AIBN) as the initiator. Evaluated by static, kinetic, and bonding capacity adsorption tests, the polymer exhibited a special selective rebinding to artemisinin. Scatchard analysis revealed that two different binding sites were formed in the polymers. The novel imprinted polymer was used as a solid-phase extraction (SPE) sorbent for the extraction of artemisinin from Artemisia annua L., followed by HPLC-UV analysis. The maximum static adsorption capacity of the artemisinin-imprinted sorbent for artemisinin was 8.46 mg g-1.The application of artemisinin-imprinted polymers with high affinity and excellent selectivity toward artemisinin in SPE might offer a novel method for the enrichment and determination of the active ingredient in Chinese medicine
Template and target information: artemisinin
Author keywords: Artemisinin, molecularly imprinted polymer, Solid-phase extraction


  Eat, sleep, imprint, repeat shirt  SMI logo mug  Man of proper-tea mug in green






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner