Book title: Chiral Separations, Methods and Protocols
Editors: Scriba GKE
Publisher: Humana Press
ISBN: ISBN (hardcover) 978-1-62703-262-9 ISBN (e-book) 978-1-62703-263-6
Series title: Methods in Molecular Biology
Volume number: 970
Abstract: A generalized preparation protocol for open tubular (OT) molecular imprinted polymer (MIP) silica capillary columns for chiral separations in capillary electrochromatography (CEC) is described. For -different chiral molecules the same general composition of the MIP reaction mixture can be used except for the choice of the specific template. This protocol is valid for a variety of templates including acidic, basic, and neutral molecules, enabling formation of rugged and porous thin MIP layers on the inner surface of the capillary resulting in columns with high chiral separation efficiencies if the template has a good chiral recognition susceptibility.
Template and target information: Review - MIPs in open tubuar electrochromatography