MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Mirzaei M, Najafabadi SAH, Abdouss M, Azodi-Deilami S, Asadi E, Hosseini MRM, Piramoon M
Article Title: Preparation and utilization of microporous molecularly imprinted polymer for sustained release of tetracycline.
Publication date: 2013
Journal: Journal of Applied Polymer Science
Volume: 128
Issue: (3)
Page numbers: 1557-1562.
DOI: 10.1002/app.38311

Abstract: A polyacrylate tetracycline (TC) selective microporous molecularly imprinted polymer was prepared in three different porogenic solvents (chloroform, acetonitrile, and methanol) via precipitation polymerization, using methacrylic acid monomer, ethylene glycol dimethacrylate crosslinker, and TC as template. In all three solvents this method produced microporous particles in the scale range (200 - 400 nm), simply, quickly, cleanly, and in good yield. The effect of polarity of porogenic solvents on binding capacity was investigated. The imprinted polymer prepared in chloroform gave much higher binding capacity (KD = 198.6) for TC than the polymers prepared in acetonitrile (KD = 133.2) or methanol (KD = 104.7). The selectivity of imprinted polymers was evaluated by rebinding other structurally similar compounds. The results clearly indicated that the imprinted acrylate polymer exhibits an excellent selectivity toward TC, and has better ability to control the release of TC than the non-imprinted polymer. 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Template and target information: tetracycline, TC
Author keywords: biopolymers and renewable polymers, drug delivery systems, porous materials, molecular imprinting, nanoparticles, nanowires and nanocrystals

  Mister Benzene Comic Strip shirt  Chemistry peptide mug  Beach bunny periodic table shirt

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner