Abstract: Preparation of chlorogenic acid (CGA) imprinted polymer based on the surface imprinting technique was carried out by using nano-TiO2 as sacrificial support with CGA as template, MAA, EGDMA and AIBN as functional monomer, cross-linker and initiator, respectively. Structural characterization was performed by FTIR and SEM analysis. Static adsorption of the template on the polymers was investigated. The results indicated strong adsorption capability and higher adsorption selectivity (relative selectivity coefficient of 3.353) for the hollow molecularly imprinted polymer (H-MIP) toward the template molecule. Freundlich model was shown better than Langmuir model to describe isotherm adsorption behavior of H-MIP toward the template. This H-MIP also revealed good adsorption capability when it was utilized in solid phase micro-enrichment of chlorogenic acid from the methanol extract of Eucommia ulmoides.
Template and target information: chlorogenic acid, CGA
Author keywords: Molecularly imprinted polymers, surface imprinting, Nano-TiO2, adsorption