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Reference type: Journal
Authors: Tong YJ, Li HD, Guan HM, Zhao JM, Majeed S, Anjum S, Liang F, Xu GB
Article Title: Electrochemical cholesterol sensor based on carbon nanotube@molecularly imprinted polymer modified ceramic carbon electrode.
Publication date: 2013
Journal: Biosensors and Bioelectronics
Volume: 47
Page numbers: 553-558.
DOI: 10.1016/j.bios.2013.03.072
Alternative URL: http://www.sciencedirect.com/science/article/pii/S095656631300242X

Abstract: A monolithic molecular imprinting sensor based on ceramic carbon electrode (CCE) has been reported. The sensor can be renewed simply by smoothing. It was fabricated by thoroughly mixing multiwalled carbon nanotube@molecularly imprinted polymer (MWCNT@MIP), graphite powder, and silicon alkoxide, and then packing the resulting complex mixture of components firmly into the electrode cavity of a Teflon sleeve. The incorporated MWCNT@MIP in CCEs functioned as a recognition element for cholesterol determination. The MWCNT@MIP-CCEs were tested in the presence or absence of cholesterol by cyclic voltammetry and linear sweep voltammetry. The cholesterol sensor has excellent sensitivity with a linear range of 10 - 300 nM and a detection limit of 1 nM (S/N=3). The monolithic molecular imprinting sensor exhibits good stability, high sensitivity, and user-friendly reusability for cholesterol determination. This study shows that CCE is a promising matrix for MIP sensors
Template and target information: cholesterol
Author keywords: Carbon nanotube, Ceramic carbon electrode, cholesterol, Molecularly imprinted polymers, Surface Molecularly Imprinting

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