MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Pichon V, Bouzige M, Miege C, Hennion MC
Article Title: Immunosorbents: natural molecular recognition materials for sample preparation of complex environmental matrices.
Publication date: 1999
Journal: TrAC Trends in Analytical Chemistry
Volume: 18
Issue: (3)
Page numbers: 219-235.
DOI: 10.1016/S0165-9936(98)00120-4

Abstract: Immunosorbents are solid-phase extraction sorbents which are based upon molecular recognition using natural antibodies and allow a high degree of molecular selectivity. Extraction, concentration and isolation of complex aqueous environmental samples are possible in a single step from large volumes of sample. Immunoaffinity extraction can be combined with LC, in both off-line and on-line modes, thus providing a totally automated device. Its application to extracts from solid samples is solvent-free and simpler than any other clean- up procedures. The high degree of purification permits an efficient coupling with GC-MS or LC-MS. Single analytes can be targeted, and the cross-reactivity of the antibodies has been exploited with target groups of structurally related analytes, including metabolites. Several class-selective immunosorbents have been optimised for the trapping of groups of pesticides and priority industrial organic pollutants. Immunosorbents are robust, and validation studies using certified reference materials have demonstrated their reliability, They are in a more advanced stage than artificial molecularly imprinted materials, and are now moving from the laboratory stage to commercialisation. (C) 1999 Elsevier Science B.V. All rights reserved

  Periodic table Soup - the chemical formula for soup apron  Mug featuring the name Valerie spelled out in the single letter amino acid code  Meerkat somebody mention coffee mug

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner