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Reference type: Journal
Authors: Song RY, Hu XL, Guan P, Yin YN, Zhu L
Article Title: Preparation and properties of molecularly imprinted polymer microspheres for erythromycin.
Publication date: 2013
Journal: Ion Exchange and Adsorption
Volume: 29
Issue: (2)
Page numbers: 97-107.

Abstract: The molecularly imprinted polymer microspheres (EM-MIPMs) were prepared via suspension polymerization by using erythromycin (EM) as template molecule, methacrylic acid (MAA) as functional monomer and ethylene glycol dimethacrylate (EDMA) as cross-linker in aqueous phase. The morphological of the microspheres were observed by scanning electron microscopy (SEM). The effects of dispersant concentration, water/oil ratio and agitating rate on the sizes and size distribution of EM-MIPMs were investigated, and the polymerization process was also optimized. Subsequently, the molecule recognition and selectivity properties of the microspheres were evaluated. The results showed that the diameter of EM-MIPMs could be controlled between 40 μm and 130 μm. The EM-MIPMs exhibited a considerable capability of molecule recognition and selectivity for the template molecule with separation factor 1.83. In addition, dynamic adsorption experiments demonstrated that the saturated adsorption capacity of EM was up to 42.59 μmol/g
Template and target information: erythromycin, EM
Author keywords: Erythromycin, molecular imprinting, Molecule recognition, Polymer microspheres, size distribution


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