MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Cao H, Xu F, Li DX, Zhang XG, Yu JS
Article Title: Preparation and performance valuation of high selective molecularly imprinted polymers for malachite green.
Publication date: 2013
Journal: Research on Chemical Intermediates
Volume: 39
Issue: (6)
Page numbers: 2321-2337.
DOI: 10.1007/s11164-012-0759-7

Abstract: Molecular imprinting is a technology that facilitates the production of artificial receptors toward compounds of interest. In this study, we prepared a series of molecularly imprinted polymers (MIPs) by precipitation polymerization for the purpose of binding specifically to malachite green (MG). The presence of monomerūtemplate solution complexes in non-covalent MIPs systems had been verified by UV-spectrometric detection and molecular dynamics simulations. The synthesized parameters were, respectively, optimized and the optimal conditions for the efficient adsorption property were as follows: template: MG, 1 mmol; functional monomer: methacrylic acid (MAA), 8 mmol; cross-linker: ethylene glycol dimethacryllate, 16 mmol; and porogen: acetonitrile, 30 mL. Fourier transform infrared spectroscopy and nitrogen adsorption experiments were used to characterize the MIPs. Scatchard analysis was used for estimation of the dissociation constants and maximum amounts of binding sites. The polymer based on MAA had two classes of heterogeneous binding sites characterized by two values of KD and Bmax: KD = 14.10 μmol L-1 and Bmax = 1.37 μmol g-1 for the higher affinity binding sites, and KD = 384.62 μmol L-1 and Bmax = 24.77 μmol g-1 for the lower affinity binding sites. The specificity of MIPs on SPE column was evaluated by rebinding the other structurally similar compounds. The results indicated that the imprinted polymers exhibited an excellent stereo-selectivity toward MG
Template and target information: malachite green, MG
Author keywords: Malachite green, Molecularly imprinted polymers, Preparation, characteristics

  Double Bonds spoof movie poster mug  Chemistry peptide mug  Chemists are fun customisable shirt

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner