MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Piletsky SA, Piletska EV, Karim K, Freebairn KW, Legge CH, Turner APF
Article Title: Polymer cookery: Influence of polymerization conditions on the performance of molecularly imprinted polymers.
Publication date: 2002
Journal: Macromolecules
Volume: 35
Issue: (19)
Page numbers: 7499-7504.
DOI: 10.1021/ma0205562

Abstract: A set of polymers has been imprinted with (-)-ephedrine at six different temperatures, ranging from -30 to +80 degreesC. Polymer affinity and specificity were observed to be strongly dependent on the polymerization temperature. The experimental results suggest that the polymer is able to "memorize" the temperature used in the polymerization process in a manner similar to previously documented MIP "memory" effects for the template and polymerization solvent. In a study of the effect of temperature on retention and selectivity in HPLC (using the MIP as a column packing), a clear gradient change in the Van't Hoff plots was observed at 20-30 degreesC. This indicates a transition in binding mechanism from exothermic at higher temperatures to endothermic at lower temperatures. These results, supported by the evidence of template-induced MIP swelling, are interpreted in terms of desolvation and conformational changes in the polymers induced by the interaction with the template

  Shirt featuring the name Sergey spelled out in symbols of the chemical elements  Mug featuring the name Kal spelled out in the single letter amino acid code  Perpetual student shirt

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner