MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Moreira FTC, Dutra RAF, Noronha JPC, Sales MGF
Article Title: Electrochemical biosensor based on biomimetic material for myoglobin detection.
Publication date: 2013
Journal: Electrochimica Acta
Volume: 107
Page numbers: 481-487.
DOI: 10.1016/j.electacta.2013.06.061
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0013468613011675

Abstract: A novel reusable molecularly imprinted polymer (MIP) assembled on a polymeric layer of carboxylated poly(vinyl chloride) (PVCCOOH) for myoglobin (Myo) detection was developed. This polymer was casted on the gold working area of a screen printed electrode (Au-SPE), creating a novel disposable device relying on plastic antibodies. Electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV) and Fourier transform infrared spectroscopy (FTIR) studies confirmed the surface modification. The MIP/Au-SPE devices displayed a linear behaviour in EIS from 0.852 to 4.26 μg mL-1, of positive slope 6.50 1.48 (k[Omega] mL μg-1). The limit of detection was 2.25 μg mL-1. Square wave voltammetric (SWV) assays were made in parallel and showed linear responses between 1.1 and 2.98 μg mL-1. A current decrease was observed against Myo concentration, producing average slopes of -0.28 0.038 μA mL μg-1. MIP/Au-SPE also showed good results in terms of selectivity. The error% found for each interfering species were 7% for troponin T (TnT), 11% for bovine serum albumin (BSA) and 2% for creatine kinase MB (CKMB), respectively. Overall, the technical modification over the Au-SPE was found a suitable approach for screening Myo in biological fluids
Template and target information: protein, myoglobin, Myo
Author keywords: biosensor, Surface molecular imprint, Screen printed electrodes, sensor, myoglobin


  Mug featuring the name Felismina spelled out in symbols of the chemical elements  Scientist peptide mug  I shop perodically customisable tote bag

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner