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Reference type: Journal
Authors: Queiroz SCN, Collins CH, Jardim ICSF
Article Title: Methods of extraction and/or concentration of compounds found in biological fluids for subsequent chromatographic determination.
Publication date: 2001
Journal: Quimica Nova
Volume: 24
Issue: (1)
Page numbers: 68-76.
DOI: 10.1590/S0100-40422001000100013

Abstract: When organic compounds present in biological fluids are analysed by chromatographic methods, it is generally necessary to carry out a prior sample preparation due the high complexity of this type of sample, especially when the compounds to be determinated are found in very low concentrations. This article describes;some of the principal methods for sample preparation in analyses of substances present in biological fluids. The methods include liquid-liquid extraction, solid phase extraction, supercritical fluid extraction and extraction using solid and liquid membranes. The advantages and disadvantages of these methods are discussed


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